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Features include: Edema, Seizure, Hypertension, and Protein in the urine (proteinuria) and 3 more.
Organ System | Phenotype Count | Example Features |
|---|---|---|
Brain and nerves | 1 | Seizure |
Heart and blood vessels |
Biomarker and diagnostic research for preeclampsia/eclampsia 1 has been reported in the published literature.
132 clinical trials registered, 69 recruiting. Interventions under study include other interventions, drug therapy, medical devices, and procedural interventions. Pipeline includes 10 PHASE4, 6 PHASE3, 4 PHASE2. Research is sponsored by a mix of industry and academic institutions.
NCT ID | Title | Phase | Sponsor | Status |
|---|---|---|---|---|
[NCT07218237](https://clinicaltrials.gov/study/NCT07218237) |
Data assembled from 5 of 12 sources · Last updated Sep 19, 2026, 6:00 AM UTC
Online Mendelian Inheritance in Man
Genetic and Rare Diseases Info Center
Hypertension |
Kidneys and urinary system | 1 | Protein in the urine (proteinuria) |
Growth and development | 1 | Intrauterine growth retardation |
Blood and immune system | 1 | Low platelet count (thrombocytopenia) |
Digestive system | 1 | Elevated circulating hepatic transaminase concentration |
Lab test results | 1 | Elevated circulating hepatic transaminase concentration |
Mindfulness and Wearable Biosensors to Prevent Hypertensive Disorders of Pregnancy |
NA |
Medical College of Wisconsin |
RECRUITING |
[NCT06858345](https://clinicaltrials.gov/study/NCT06858345) | Study of Maternal and Fetal Cardiovascular Function in Hypertensive States of Pregnancy | — | Fundacion para la Formacion e Investigacion Sanitarias de la Region de Murcia | RECRUITING |
[NCT06953115](https://clinicaltrials.gov/study/NCT06953115) | Vagal Stimulation Therapy and Preeclampsia | NA | Fundación Internacional René Mey | RECRUITING |
[NCT05287321](https://clinicaltrials.gov/study/NCT05287321) | The Efficacy of Aspirin Combined With Hydroxychloroquine Treatment in High Risk Pregnancies for Preeclampsia | PHASE3 | Yoo-min Kim | RECRUITING |
[NCT07084727](https://clinicaltrials.gov/study/NCT07084727) | Identifying Biomarkers for Endothelial Dysfunction in Women With Preeclampsia | NA | University Hospital, Antwerp | RECRUITING |
54 publications have been identified in PubMed for preeclampsia/eclampsia 1. Research spans Case Report / Case Series (39%), Epidemiology / Natural History (33%), and Review / Meta-Analysis (13%).
Research Type | Count | % of Total |
|---|---|---|
Patient case studies | 21 | 39% |
Disease patterns and progression | 18 | 33% |
Research summaries | 7 | 13% |
Clinical study results | 3 | 6% |
Testing and diagnosis research | 2 | 4% |
Laboratory research | 2 | 4% |
Other research | 1 | 2% |
Ayoub EH (2026). [PMID: 41788088](https://pubmed.ncbi.nlm.nih.gov/41788088/). *Cureus*. [Case Report / Case Series]
Zhang CL (2026). [PMID: 41765649](https://pubmed.ncbi.nlm.nih.gov/41765649/). *Zhonghua fu chan ke za zhi*. [Epidemiology / Natural History]
Rachidi H (2026). [PMID: 42006511](https://pubmed.ncbi.nlm.nih.gov/42006511/). *Cureus*. [Case Report / Case Series]
Goshu MT (2026). [PMID: 42057011](https://pubmed.ncbi.nlm.nih.gov/42057011/). *BMC Pregnancy Childbirth*. [Case Report / Case Series]
Stern EM (2026). [PMID: 35015414](https://pubmed.ncbi.nlm.nih.gov/35015414/). *Unknown Journal*. [Case Report / Case Series]
Li H (2026). [PMID: 41909338](https://pubmed.ncbi.nlm.nih.gov/41909338/). *Cureus*. [Case Report / Case Series]
Patil AS (2026). [PMID: 42005249](https://pubmed.ncbi.nlm.nih.gov/42005249/). *Cureus*. [Clinical Trial Publication]
Sun C (2026). [PMID: 42165172](https://pubmed.ncbi.nlm.nih.gov/42165172/). *J Clin Hypertens (Greenwich)*. [Epidemiology / Natural History]
Stavros S (2026). [PMID: 41900980](https://pubmed.ncbi.nlm.nih.gov/41900980/). *Life (Basel, Switzerland)*. [Review / Meta-Analysis]
Anbu R (2026). [PMID: 42116944](https://pubmed.ncbi.nlm.nih.gov/42116944/). *Cureus*. [Case Report / Case Series]
AI-curated news mentioning preeclampsia/eclampsia 1
Updated May 29, 2026
A systematic review explores the role of inflammasome biology in preeclampsia, highlighting mechanisms such as Bnip3-mitophagy and Nlrp1-driven placental injury. This research provides a translational roadmap for understanding the pathophysiology of preeclampsia.
A recent meta-analysis published in PubMed examines the incidence, management, and outcomes of eclampsia across multiple countries. This study aggregates individual participant data to provide insights into the condition's global impact.
A case report highlights profound hyponatraemia as a rare and complex presentation in early-onset preeclampsia. This finding may prompt further investigation into the underlying mechanisms and management strategies for affected patients.