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preeclampsia/eclampsia 4 - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

preeclampsia/eclampsia 4

MONDO:0012266

Also known as:Preeclampsia/eclampsia type 4STOX1 preeclampsiapreeclampsia caused by mutation in STOX1

Overview

Any preeclampsia in which the cause of the disease is a mutation in the STOX1 gene.

GeneticsPolygenic (multifactorial) · STOX1 (chr 10)

Genetic Landscape

STOX1 function has not been fully characterized.

Preeclampsia/eclampsia 4 is associated with mutations in the STOX1 gene on chromosome 10.

Diagnosis

Genetic testing for STOX1 is available. Testing is considered confirmatory for diagnosis.

Biomarker and diagnostic research for preeclampsia/eclampsia 4 has been reported in the published literature.

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

No clinical trials have been registered for preeclampsia/eclampsia 4.

96 publications have been identified in PubMed for preeclampsia/eclampsia 4. Research spans Epidemiology / Natural History (54%), Clinical Trial Publication (18%), and Review / Meta-Analysis (15%).

Research Type	Count	% of Total
Disease patterns and progression	52	54%

Data assembled from 4 of 12 sources · Last updated Sep 19, 2026, 3:30 AM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

OMIM

Online Mendelian Inheritance in Man

OMIM:609404

GARD

Genetic and Rare Diseases Info Center

GARD:18392

Questions for Your Care Team

→Should I pursue genetic testing for STOX1, and what would the results mean for my family?
→Are there specialists or centers of excellence for this condition in my area?
→Is there a patient registry I should consider joining?

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preeclampsia/eclampsia 4

Overview

Genetic Landscape

Diagnosis

Research Landscape

Medical References

External Resources

OMIM

GARD

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Questions for Your Care Team

Questions for Your Care Team

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