Kisho

Kisho is an information platform, not a medical provider. Nothing on this site constitutes medical advice, diagnosis, or treatment recommendations. All content is aggregated from publicly available sources (including ClinicalTrials.gov, PubMed, FDA.gov, and Orphanet) and is provided for informational purposes only. Clinical trial eligibility, treatment decisions, and any health-related actions should always be discussed with a qualified healthcare professional. Kisho does not endorse any specific therapy, organization, or clinical trial. Terms of use · Privacy policy

scleroderma, familial progressive - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

scleroderma, familial progressive

MONDO:0008418

Also known as:Crest syndromesystemic sclerosis, susceptibility to

Find Clinical TrialsTrials

Overview

GeneticsAutosomal dominant

Clinical Trials1 registered · 1 recruiting

Clinical Presentation

Features include: Calcinosis, Scleroderma, Abnormality of chromosome stability, and Sclerodactyly and 3 more.

Organ System	Phenotype Count	Example Features
Skin	1	Telangiectasia

Explore clinical features

Diagnosis

Biomarker and diagnostic research for scleroderma, familial progressive has been reported in the published literature.

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

1 clinical trial registered, 1 recruiting. Interventions under study include drug therapy. Pipeline includes 1 PHASE2. Research is primarily industry-sponsored.

143 publications have been identified in PubMed for scleroderma, familial progressive. Research spans Review / Meta-Analysis (30%), Epidemiology / Natural History (28%), and Case Report / Case Series (19%).

Research Type	Count	% of Total
Research summaries	38	30%

Data assembled from 5 of 12 sources · Last updated Sep 19, 2026, 4:28 PM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

OMIM

Online Mendelian Inheritance in Man

OMIM:181750

Questions for Your Care Team

→Are any of the 1 active clinical trial a good fit for my situation?
→Are there specialists or centers of excellence for this condition in my area?
→Is there a patient registry I should consider joining?

← Back to All Diseases

Kisho

scleroderma, familial progressive

Overview

Clinical Presentation

Explore clinical features

Diagnosis

Research Landscape

Medical References

External Resources

OMIM

Questions for Your Care Team

Questions for Your Care Team

Recent Publications

Latest News & Developments

Navigating the Unknown: Scleroderma Renal Crisis and a Fatal Cardiac Complication in a Young Patient With MCTD With Coexisting Anti-U3 RNP and Anti-RNA Polymerase III Antibodies.

Scleroderma Renal Crisis in Mixed Connective Tissue Disease.

Cellular and molecular dysregulation of the esophageal epithelium in systemic sclerosis.

scleroderma, familial progressive

Overview

Clinical Presentation

Explore clinical features

Diagnosis

Research Landscape

Medical References

External Resources

OMIM

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

Recent Publications

Latest News & Developments

Navigating the Unknown: Scleroderma Renal Crisis and a Fatal Cardiac Complication in a Young Patient With MCTD With Coexisting Anti-U3 RNP and Anti-RNA Polymerase III Antibodies.

Scleroderma Renal Crisis in Mixed Connective Tissue Disease.

Cellular and molecular dysregulation of the esophageal epithelium in systemic sclerosis.