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split hand, bilateral - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

split hand, bilateral

MONDO:0017512

Overview

Split hand, bilateral is a rare, non-syndromic limb reduction defect, clinically and genetically heterogeneous, characterized by bilateral underdevelopment or absence of the central rays of the autopod, with absence of all, or just some, of the central phalanges and at least part of the associated metacarpal bones, yielding a cleft appearance of the hand. It is frequently associated with syndactyly and aplasia/hypoplasia of remaining digits and metacarpal bones. No other dysmorphic features are observed and development is appropriate for age.

Diagnosis

Biomarker and diagnostic research for split hand, bilateral has been reported in the published literature.

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

No clinical trials have been registered for split hand, bilateral.

11 publications have been identified in PubMed for split hand, bilateral. Research spans Review / Meta-Analysis (36%), Case Report / Case Series (36%), and Diagnostic / Biomarker (9%).

Research Type	Count	% of Total
Research summaries	4	36%

Data assembled from 3 of 12 sources · Last updated Sep 19, 2026, 12:47 AM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

Orphanet

European rare disease database

Orphanet:295122

Questions for Your Care Team

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split hand, bilateral

Overview

Diagnosis

Research Landscape

Medical References

External Resources

Orphanet

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

Recent Publications