Kisho

Kisho is an information platform, not a medical provider. Nothing on this site constitutes medical advice, diagnosis, or treatment recommendations. All content is aggregated from publicly available sources (including ClinicalTrials.gov, PubMed, FDA.gov, and Orphanet) and is provided for informational purposes only. Clinical trial eligibility, treatment decisions, and any health-related actions should always be discussed with a qualified healthcare professional. Kisho does not endorse any specific therapy, organization, or clinical trial. Terms of use · Privacy policy

split hand, unilateral - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

split hand, unilateral

MONDO:0017511

Overview

Split hand, unilateral is a rare, non-syndromic limb reduction defect, clinically and genetically heterogeneous, characterized by unilateral underdevelopment or absence of the central rays of the autopod, with absence of all, or just some, of the central phalanges and at least part of the associated metacarpal bones, yielding a cleft appearance of the hand. It is frequently associated with syndactyly and aplasia/hypoplasia of remaining digits and metacarpal bones. No other dysmorphic features are observed and development is appropriate for age.

ResearchLimited published research (5 articles)

Diagnosis

Biomarker and diagnostic research for split hand, unilateral has been reported in the published literature.

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

No clinical trials have been registered for split hand, unilateral.

5 publications have been identified in PubMed for split hand, unilateral. Research spans Diagnostic / Biomarker (40%), Clinical Trial Publication (40%), and Case Report / Case Series (20%).

Recent Publications

Wang B (2026). [PMID: 42051705](https://pubmed.ncbi.nlm.nih.gov/42051705/). *Front Med (Lausanne)*. [Diagnostic / Biomarker]
Farvardin H (2025). [PMID: 39620612](https://pubmed.ncbi.nlm.nih.gov/39620612/). *J Pediatr Ophthalmol Strabismus*. [Clinical Trial Publication]
Yaman A (2025). [PMID: 40270640](https://pubmed.ncbi.nlm.nih.gov/40270640/). *Turk J Phys Med Rehabil*. [Clinical Trial Publication]
Ismiarto YD (2025). [PMID: 39809051](https://pubmed.ncbi.nlm.nih.gov/39809051/). *Int J Surg Case Rep*. [Case Report / Case Series]
Zeybek SG (2024). [PMID: 38494584](https://pubmed.ncbi.nlm.nih.gov/38494584/). *Int Urol Nephrol*. [Diagnostic / Biomarker]

Data assembled from 3 of 12 sources · Last updated Sep 19, 2026, 11:52 AM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

Orphanet

European rare disease database

Orphanet:295120

Questions for Your Care Team

→Are there specialists or centers of excellence for this condition in my area?
→Is there a patient registry I should consider joining?

← Back to All Diseases

split hand, unilateral

Overview

Diagnosis

Research Landscape

Recent Publications

Medical References

External Resources

Orphanet

Related Diseases

Questions for Your Care Team

Questions for Your Care Team