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staphylococcal toxic-shock syndrome - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

staphylococcal toxic-shock syndrome

MONDO:0020545

Also known as:Staphylococcus caused toxic shock syndromeStaphylococcus toxic shock syndromestaphylococcal TSS

Overview

Staphylococcal toxic shock syndrome (staphylococcal TSS) is an acute disease mediated by the production of superantigenic toxins, characterized by high fever, skin rash followed by skin peeling, hypotension, vomiting, diarrhea and potentially leading to multisystem organ failure and caused by a Staphylococcus aureus bacterial infection.

Treatments1 FDA approved

Diagnosis

Biomarker and diagnostic research for staphylococcal toxic-shock syndrome has been reported in the published literature.

Treatment

Compiled from FDA-approved drug records, orphan drug designations, and FDA Adverse Event Reporting System (FAERS) safety data. GeneReviews management guidance is included where available.

1 FDA-approved treatment is available for staphylococcal toxic-shock syndrome, including DOPAMINE HYDROCHLORIDE (DOPAMINE HYDROCHLORIDE AND DEXTROSE, approved 1987).

Approved Therapies

Brand Name	Generic Name	Mechanism	Approved	Market Status

Prognosis

Estimated prevalence: Unknown (Unknown prevalence).

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

No clinical trials have been registered for staphylococcal toxic-shock syndrome.

125 publications have been identified in PubMed for staphylococcal toxic-shock syndrome. Research spans Epidemiology / Natural History (30%), Case Report / Case Series (23%), and Basic Science / Preclinical (22%).

Research Type	Count	% of Total
Disease patterns and progression	32	30%

Data assembled from 4 of 12 sources · Last updated Sep 19, 2026, 8:56 AM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

Orphanet

European rare disease database

Orphanet:99919

GARD

Genetic and Rare Diseases Info Center

GARD:19710

Questions for Your Care Team

→What are the benefits and potential side effects of DOPAMINE HYDROCHLORIDE AND DEXTROSE for managing staphylococcal toxic-shock syndrome?
→Are there specialists or centers of excellence for this condition in my area?
→Is there a patient registry I should consider joining?

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Kisho

staphylococcal toxic-shock syndrome

Overview

Diagnosis

Treatment

Approved Therapies

Prognosis

Research Landscape

Medical References

External Resources

Orphanet

GARD

Questions for Your Care Team

Questions for Your Care Team

Clinical Trials

Recent Publications

staphylococcal toxic-shock syndrome

Overview

Diagnosis

Treatment

Approved Therapies

Prognosis

Research Landscape

Medical References

External Resources

Orphanet

GARD

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

Clinical Trials

Recent Publications