Kisho

Kisho is an information platform, not a medical provider. Nothing on this site constitutes medical advice, diagnosis, or treatment recommendations. All content is aggregated from publicly available sources (including ClinicalTrials.gov, PubMed, FDA.gov, and Orphanet) and is provided for informational purposes only. Clinical trial eligibility, treatment decisions, and any health-related actions should always be discussed with a qualified healthcare professional. Kisho does not endorse any specific therapy, organization, or clinical trial. Terms of use · Privacy policy

streptococcal toxic-shock syndrome - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

streptococcal toxic-shock syndrome

MONDO:0020544

Also known as:Streptococcus caused toxic shock syndromeStreptococcus toxic shock syndromestreptococcal TSS

Overview

Streptococcal toxic-shock syndrome (streptococcal TSS) is an acute disease mediated by the production of superantigenic toxins characterized by the sudden onset of fever and other febrile symptoms, pain, multisystem organ involvement and potentially leading to coma, shock and death due to a Streptococcus pyogenes infection.

Treatments1 FDA approved

Diagnosis

Biomarker and diagnostic research for streptococcal toxic-shock syndrome has been reported in the published literature.

Treatment

Compiled from FDA-approved drug records, orphan drug designations, and FDA Adverse Event Reporting System (FAERS) safety data. GeneReviews management guidance is included where available.

1 FDA-approved treatment is available for streptococcal toxic-shock syndrome, including DOPAMINE HYDROCHLORIDE (DOPAMINE HYDROCHLORIDE AND DEXTROSE, approved 1987).

Approved Therapies

Brand Name	Generic Name	Mechanism	Approved	Market Status

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

No clinical trials have been registered for streptococcal toxic-shock syndrome.

192 publications have been identified in PubMed for streptococcal toxic-shock syndrome. Research spans Case Report / Case Series (54%), Epidemiology / Natural History (24%), and Review / Meta-Analysis (9%).

Research Type	Count	% of Total
Patient case studies	104	54%

Data assembled from 4 of 12 sources · Last updated Sep 19, 2026, 12:51 AM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

Orphanet

European rare disease database

Orphanet:99918

GARD

Genetic and Rare Diseases Info Center

GARD:19709

Questions for Your Care Team

→What are the benefits and potential side effects of DOPAMINE HYDROCHLORIDE AND DEXTROSE for managing streptococcal toxic-shock syndrome?
→Are there specialists or centers of excellence for this condition in my area?
→Is there a patient registry I should consider joining?

← Back to All Diseases

Kisho

streptococcal toxic-shock syndrome

Overview

Diagnosis

Treatment

Approved Therapies

Research Landscape

Medical References

External Resources

Orphanet

GARD

Questions for Your Care Team

Questions for Your Care Team

Clinical Trials

Recent Publications

Latest News & Developments

Streptococcal Toxic Shock Syndrome: Persistent Diagnostic and Therapeutic Challenges.

Periorbital necrotizing soft tissue infection due to Streptococcus pyogenes with streptococcal toxic shock syndrome: successful early structured multidisciplinary management.

streptococcal toxic-shock syndrome

Overview

Diagnosis

Treatment

Approved Therapies

Research Landscape

Medical References

External Resources

Orphanet

GARD

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

Clinical Trials

Recent Publications

Latest News & Developments

Streptococcal Toxic Shock Syndrome: Persistent Diagnostic and Therapeutic Challenges.

Periorbital necrotizing soft tissue infection due to Streptococcus pyogenes with streptococcal toxic shock syndrome: successful early structured multidisciplinary management.