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Paroxysmal hemicrania (PH) is a primary headache disorder characterized by multiple attacks of unilateral pain that occur in association with cranial autonomic symptoms. The hallmarks of this syndrome are the relative shortness of the attacks and the complete response to indomethacin therapy.
Estimated prevalence: Unknown (Unknown prevalence).
3 clinical trials registered, 2 recruiting. Interventions under study include drug therapy and other interventions. Pipeline includes 1 PHASE2, 1 PHASE1. Research is primarily sponsored by academic and government institutions.
22 publications have been identified in PubMed for paroxysmal Hemicrania. Research spans Case Report / Case Series (45%), Review / Meta-Analysis (32%), and Epidemiology / Natural History (9%).
Research Type | Count | % of Total |
|---|---|---|
Patient case studies | 10 |
Data assembled from 4 of 12 sources · Last updated Sep 18, 2026, 10:37 PM UTC
European rare disease database
Genetic and Rare Diseases Info Center
Research summaries | 7 | 32% |
Disease patterns and progression | 2 | 9% |
Other research | 1 | 5% |
Clinical study results | 1 | 5% |
Laboratory research | 1 | 5% |
Hameed S (2026). [PMID: 32491500](https://pubmed.ncbi.nlm.nih.gov/32491500/). *Unknown Journal*. [Review / Meta-Analysis]
Jaimes A (2026). [PMID: 41765128](https://pubmed.ncbi.nlm.nih.gov/41765128/). *Neurologia (Engl Ed)*. [Other]
Zwergal RM (2026). [PMID: 41717391](https://pubmed.ncbi.nlm.nih.gov/41717391/). *Pain reports*. [Case Report / Case Series]
Miller AK (2026). [PMID: 40717615](https://pubmed.ncbi.nlm.nih.gov/40717615/). *Journal of child neurology*. [Clinical Trial Publication]
Kollenburg L (2026). [PMID: 40995873](https://pubmed.ncbi.nlm.nih.gov/40995873/). *Brain : a journal of neurology*. [Basic Science / Preclinical]
Bodle J (2026). [PMID: 32644406](https://pubmed.ncbi.nlm.nih.gov/32644406/). *Unknown Journal*. [Review / Meta-Analysis]
Osiowski A (2025). [PMID: 39911098](https://pubmed.ncbi.nlm.nih.gov/39911098/). *Current opinion in neurology*. [Review / Meta-Analysis]
Hauser Chatterjee J (2025). [PMID: 40129243](https://pubmed.ncbi.nlm.nih.gov/40129243/). *Headache*. [Case Report / Case Series]
Fernandes CS (2025). [PMID: 40888687](https://pubmed.ncbi.nlm.nih.gov/40888687/). *Cephalalgia : an international journal of headache*. [Epidemiology / Natural History]
Tsai PY (2025). [PMID: 41476707](https://pubmed.ncbi.nlm.nih.gov/41476707/). *Frontiers in ophthalmology*. [Case Report / Case Series]