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Foodborne botulism is the most common form of botulism, a rare acquired neuromuscular junction disease with descending flaccid paralysis due to botulinum neurotoxins (BoNTs). It is caused by consumption of contaminated food containing BoNTs.
Features include very common findings: Xerostomia, Ptosis, Diplopia, and Dysarthria and others; and common findings: Urinary retention, Nausea and vomiting, Difficulty breathing due to muscle weakness (respiratory insufficiency due to muscle weakness), and Arrhythmia. 19 total HPO annotations.
Organ System | Phenotype Count | Example Features |
|---|---|---|
Digestive system | 5 | Diarrhea, Difficulty swallowing (dysphagia), Nausea and vomiting |
Biomarker and diagnostic research for foodborne botulism has been reported in the published literature.
Phenotype severity distribution: 14 very common features, 4 common features.
Estimated prevalence: Unknown (Unknown prevalence).
No clinical trials have been registered for foodborne botulism.
54 publications have been identified in PubMed for foodborne botulism. Research spans Case Report / Case Series (24%), Epidemiology / Natural History (22%), and Review / Meta-Analysis (19%).
Research Type | Count | % of Total |
|---|---|---|
Patient case studies | 13 | 24% |
Data assembled from 4 of 12 sources · Last updated Sep 19, 2026, 6:53 PM UTC
European rare disease database
Genetic and Rare Diseases Info Center
Brain and nerves | 4 | Dysarthria, Difficulty swallowing (dysphagia), Cranial nerve paralysis |
Eyes | 2 | Ptosis, Diplopia |
Muscles | 2 | Muscle weakness, Difficulty breathing due to muscle weakness (respiratory insufficiency due to muscle weakness) |
Kidneys and urinary system | 1 | Urinary retention |
Lungs and breathing | 1 | Difficulty breathing due to muscle weakness (respiratory insufficiency due to muscle weakness) |
Heart and blood vessels | 1 | Arrhythmia |
12 |
22% |
Research summaries | 10 | 19% |
Laboratory research | 10 | 19% |
New treatment approaches | 4 | 7% |
Testing and diagnosis research | 3 | 6% |
Other research | 2 | 4% |
Iskander M (2026). [PMID: 42181480](https://pubmed.ncbi.nlm.nih.gov/42181480/). *Cureus*. [Case Report / Case Series]
Valdezate S (2026). [PMID: 41809992](https://pubmed.ncbi.nlm.nih.gov/41809992/). *Front Cell Infect Microbiol*. [Epidemiology / Natural History]
Agnihotri S (2026). [PMID: 42159747](https://pubmed.ncbi.nlm.nih.gov/42159747/). *Arch Toxicol*. [Basic Science / Preclinical]
Zhan Y (2026). [PMID: 41958893](https://pubmed.ncbi.nlm.nih.gov/41958893/). *China CDC Wkly*. [Epidemiology / Natural History]
Liu Z (2026). [PMID: 42035854](https://pubmed.ncbi.nlm.nih.gov/42035854/). *Int J Biol Macromol*. [Basic Science / Preclinical]
Galassi FM (2026). [PMID: 42201620](https://pubmed.ncbi.nlm.nih.gov/42201620/). *Intern Emerg Med*. [Epidemiology / Natural History]
Soleymanpour K (2026). [PMID: 41788389](https://pubmed.ncbi.nlm.nih.gov/41788389/). *Infez Med*. [Review / Meta-Analysis]
Kihara K (2026). [PMID: 42156031](https://pubmed.ncbi.nlm.nih.gov/42156031/). *Brain Nerve*. [Review / Meta-Analysis]
Liu S (2026). [PMID: 40766982](https://pubmed.ncbi.nlm.nih.gov/40766982/). *Foodborne Pathog Dis*. [Basic Science / Preclinical]
Shang R (2026). [PMID: 41701083](https://pubmed.ncbi.nlm.nih.gov/41701083/). *Foodborne Pathog Dis*. [Case Report / Case Series]