Kisho

Kisho is an information platform, not a medical provider. Nothing on this site constitutes medical advice, diagnosis, or treatment recommendations. All content is aggregated from publicly available sources (including ClinicalTrials.gov, PubMed, FDA.gov, and Orphanet) and is provided for informational purposes only. Clinical trial eligibility, treatment decisions, and any health-related actions should always be discussed with a qualified healthcare professional. Kisho does not endorse any specific therapy, organization, or clinical trial. Terms of use · Privacy policy

intestinal botulism - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

intestinal botulism

MONDO:0015805

Also known as:intestinal colonisation botulismintestinal colonization botulismintestinal toxaemia botulism

Overview

A rare form of botulism, a rare acquired neuromuscular junction disease with descending flaccid paralysis caused by botulinum neurotoxins (BoNTs), and is due to intestinal colonization by Clostridium botulinum leading to toxin-mediated infection with toxemia. The disease affects infants (infant botulism) and very rarely adults (adult intestinal botulism).

Clinical Presentation

Built from Human Phenotype Ontology (HPO) phenotype annotations and GeneReviews clinical descriptions. Features represent findings documented across known cases — not an exhaustive list of possible symptoms.

Features include very common findings: Ptosis, Diplopia, Low muscle tone (hypotonia), and Dysarthria and others; and common findings: Xerostomia, Diarrhea, and Nausea and vomiting. 12 total HPO annotations.

Organ System	Phenotype Count	Example Features
Brain and nerves	3	Dysarthria, Difficulty swallowing (dysphagia), Cranial nerve paralysis

Prognosis

Phenotype severity distribution: 7 very common features, 3 common features.

Estimated prevalence: Unknown (Unknown prevalence).

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

No clinical trials have been registered for intestinal botulism.

14 publications have been identified in PubMed for intestinal botulism. Research spans Case Report / Case Series (50%), Review / Meta-Analysis (36%), and Epidemiology / Natural History (14%).

Research Type	Count	% of Total
Patient case studies	7	50%

Data assembled from 4 of 12 sources · Last updated Oct 3, 2026, 8:09 PM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

Orphanet

European rare disease database

Orphanet:178481

GARD

Genetic and Rare Diseases Info Center

GARD:20151

Questions for Your Care Team

→Are there specialists or centers of excellence for this condition in my area?
→Is there a patient registry I should consider joining?

← Back to All Diseases

Kisho

intestinal botulism

Overview

Clinical Presentation

Prognosis

Research Landscape

Medical References

External Resources

Orphanet

GARD

Questions for Your Care Team

Questions for Your Care Team

Explore clinical features

Recent Publications

intestinal botulism

Overview

Clinical Presentation

Prognosis

Research Landscape

Medical References

External Resources

Orphanet

GARD

Subtypes

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

Explore clinical features

Recent Publications